What it does Kills C. acnes; can be drying. Performance by skin type & concern Skin typeConcernEfficacySafety Oily acne 90/100 55/100 Pairs well & pairs poorly with Synergies Adapalene Established acne combo when applied at the right cadence. Conflicts Retinol medium BPO can oxidize retinol; alternate AM/PM rather than mixing.